Eppendorf ThermoMixer® C

Improve your assay results by dry incubation and mixing of your samples simultaneously: The Eppendorf ThermoMixer C is for heating, cooling, and mixing almost any of your lab vessels. Reliable prevention of condensate formation in small vessels can be achieved with the heated lid Eppendorf ThermoTop (optional). More information

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Product Information

You need everything? The Eppendorf ThermoMixer C combines excellent mixing performance with excellent temperature control to ensure complete, dependable and reproducible test results. Improve your assay results by mixing and incubating samples at the same time. The Eppendorf ThermoMixer C convinces users with its quick and easy-to-exchange SmartBlocks for all common lab vessels, new and improved program functions, and high level of stability for every mixing frequency. There is almost no limit to the variety of applications waiting for you!

Facing irregular mixing results?

Reliable sample mixing is far beyond simple mixing, especially when talking about microliter volumes. After decades of offering mixing devices, we found a way to expand reliable mixing performance to the microliter scale:

Eppendorf ThermoMixer® C



The 2DMix–Control technology mixes liquids in a controlled, circular movement. Orbital circular paths with a diameter of 3 mm and up to 3,000 rpm: Generates excellent mixing performance, even for challenging samples. The ThermoMixer C provides enough mixing power to handle also challenging mixing tasks. Most samples are efficiently mixed within less than a minute independent of vessel geometry or sample properties.

Eppendorf ThermoMixer® C

Using different vessel formats?

A wide varity of Eppendorf SmartBlocks are available for the Eppendorf ThermoMixer C. These thermoblocks offer the utmost flexibility for use of all common vessel and plate formats.

› Fast and simple block exchange due to Eppendorf QuickRelease
› Optimized block design guarantees maximum temperature transfer to the sample
› Individually sensor‐controlled Eppendorf SmartBlocks allow for block‐specific calibration

Eppendorf ThermoMixer® C

Tired of condensation in your tubes?

We combined the Eppendorf ThermoMixer with the PCR cycler approach of a heated lid and generated the Eppendorf ThermoTop®. The outstanding Eppendorf condens.protect technology reliably prevents condensation within the tube lid – sample concentrations are consistent for the incubation time.
In addition, the temperature homogeneity is further improved. Get optimal sample reaction conditions to produce optimal results.

› Efficient and reliable condensation prevention on tube lids for safe sample heating
› Get constant reaction conditions for optimal enzymatic performance within your sample
› Wireless connection with automatic recognition and operation for user-friendly handling

Eppendorf ThermoMixer® C

Missing a second temperature for an incubation at 37 °C or 95 °C at your Eppendorf ThermoMixer?

The Eppendorf SmartExtender offers a comfortable incubation tool which can easily be used as an add-on to your existing Eppendorf SmartBlocks and the Eppendorf ThermoMixer C/Fx as well as Eppendorf ThermoStat C. Up to 12 vessels (1.5 mL) can be heated up for a higher throughput and higher flexibility in your lab. The independent heating function for the second temperature enables a parallel usage of an Eppendorf SmartBlock and the SmartExtender. The Eppendorf SmartBlock at the center can still be used for heating, cooling, and mixing.

Eppendorf ThermoMixer® C

Annoyed by uncomfortable handling?

Ergonomics is far beyond the »ergonomically designed chair«. Eppendorf started to optimize the laboratory devices regarding ergonomics already in the early 1970s.
In 2003, we started the PhysioCare Concept, focusing on ergonomic liquid handling devices like our pipettes.
Nowadays, the Eppendorf PhysioCare Concept is broaden up to include further laboratory products as a holistic solution to harmonize the workflow in your laboratory with your health and well-being, e.g. for the Eppendorf ThermoMixer:
› Eppendorf QuickRelease for easy and fast block exchange
› Insulated SmartBlock for safe gripping / no burning of fingers
› Direct keys for convenient handling
› Small footprint to enable position in direct arm reach at your bench
› Standardized »user-interface concept« for intuitive handling of devices

Further information about the Eppendorf PhysioCare Concept:

Eppendorf ThermoMixer® C

Struggling with paper-based documentation?

The eLABJournal Electronic Lab Notebook offers an intuitive and flexible solution to document research and track research data like workflow processes where the Eppendorf ThermoMixer is involved. Improve efficiency when documenting, organizing, searching, and archiving collected data. With the free eLABJournal add-ons, you can extend the functionality of eLABJournal to a fully integrated Laboratory Information Management System.

Start a free 30-day trial!
Visit www.eLABJournal.com

Eppendorf ThermoMixer® C


  • Mixing, heating, and cooling in one instrument for high flexibility
  • All common vessels and plate formats from 5 µL to 50 mL by different Eppendorf SmartBlocks™ for standard applications
  • Excellent 2DMix-Control technology results in excellent sample mixing
  • Anti-spill technology prevents lid wetting and cross-contamination
  • Increased mixing frequency of up to 3,000 rpm for effective sample mixing
  • Excellent temperature management for maximum temperature accuracy, resulting in safe handling
  • Compatible with Eppendorf ThermoTop® (condens.protect®) for condensation-free sample handling (for Eppendorf SmartBlocks up to 2.0 mL)
  • Predefined program keys and clearly arranged menu guides enable simple and intuitive operations
  • Freely programmable program keys for individual optimization
  • Eppendorf PhysioCare Concept® provides ergonomic design and operation


  • Plasmid/RNA/DNA purification
  • cDNA synthesis
  • Extraction of DNA fragments from agarose gels
  • Enzymatic reactions (e.g., DNA restriction digestion, Proteinase K digestion and ligation)
  • Transformation of bacteria strains and plasmids
  • Denaturation of DNA, RNA, and proteins
  • Labeling of DNA, RNA, and proteins
  • Bacterial growth in microreaction vessels, conical tubes, and Deepwell Plates
  • Lysis reactions at 100 °C
  • Mixing of PCR setups
 Eppendorf ThermoMixer® C
Max. speed3,000 rpm1
Mixing and vortexing radius1.5 mm
Mixing frequency300 – 3,000 rpm1
Mixing orbit3 mm
Temperature accuracyMax. ±0.5 °C at 20 – 45 °C
Temperature settings1 °C / 100 °C
Timer15 sec to 99:30 h, continuous
Heating rateMax. 7 °C/min (when using SmartBlock plates)1
Cooling rateMax. 2.5 °C/min between 100 °C and RT
InterfacesUSB interface
Power supply220 – 240 V, 50 – 60 Hz
Max. power consumption200 W
Dimensions (W × D × H)20.6 × 30.4 × 13.6 cm
Weight w/o accessories6.3 kg
Temperature rangeMin: 15 °C below RT, max: 100 °C1
1depends on SmartBlock used
Eppendorf ThermoMixer® C
Video: Eppendorf ThermoMixer® C – Video – ThermoTop
Eppendorf ThermoMixer® C
Video: Eppendorf ThermoMixer® C – Video – Pellet resuspension
Eppendorf ThermoMixer® C
Video: Eppendorf ThermoMixer® C – Video – QuickRelease
Eppendorf ThermoMixer® C
Video: Eppendorf ThermoMixer® C – Video – Multiple Talent
Eppendorf ThermoMixer® C
Video: Eppendorf ThermoMixer® C – Video – The Eppendorf - Reliable experiments by condens.protect®

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